Mancozeb: A solid shield for plants

Mancozeb: A solid shield for plants

Mancozeb is a broad-spectrum fungicide created by combining two manganese and zinc salts belonging to the dithiocarbamate group, with the chemical formula (C₄H₆MnN₂S₄)x(Zn)y.

IUPAC name: Manganese ethylenebis(dithiocarbâmte) (polymeric) complex with zinc salt.

▪️Appearance: It is a greyish-yellow powder, stable, insoluble in water and organic solvents, and only decomposes at high temperatures by moisture and acid. In addition to yellow, Mancozeb can also have other colors such as green or blue due to the addition of additives, which also make Mancozeb soluble in water, making it easier to use. Mancozeb can produce flammable products upon decomposition. It is also unstable in acidic conditions.

▪️Common formulation forms: Mancozeb 85% Tech, 75%, 80% WG, WP

▪️Mechanism of action:

- Mancozeb is a non-systemic fungicide with protective action. It inhibits the activity of enzymes in fungi by forming complexes with metal-containing enzymes, including those involved in ATP production.

- Mancozeb affects various organ systems. Its primary mechanism of toxicity is through skin contact, leading to contact dermatitis and skin sensitization. Mancozeb has also been shown to have teratogenic and reproductive effects. Exposure to Mancozeb also alters reproductive and endocrine structures, leading to decreased fertility.

- Animals orally exposed to Mancozeb showed thyroid hyperplasia, probably due to its ability to inhibit the synthesis of thyroxine. Additionally, exposure to Mancozeb also causes neurotoxicity through an unknown mechanism.

- Similar to Maneb, Mancozeb also has chelating properties, allowing it to interfere with some enzyme systems containing metals such as zinc, copper, and iron (e.g., dopamine β-hydroxylase).

▪️Advantages:

- Kills a wide range of fungi, up to 400 types of fungi on plants such as: Late blight, leaf spots, anthracnose, rust that harms ornamental plants, rapid death - slow death, crab eye spots, oozing, fruit rot...

- High disease prevention, low pesticide resistance.

- Good and long-lasting adhesion on leaf surfaces to prevent fungal invasion.

- Can be combined with most other pesticides like Metalaxyl or Cymoxanil...

- Safe for plants and animals, short preharvest interval (PHI) (under 15 days).

- Cheap, reasonable price, easy to use.

▪️Disadvantages:

- Only effective when in direct contact with fungus, not systemic.

- Causes chronic skin diseases if exposed frequently to the pesticides.

- Not for use on vegetables and safe clean foods.

▫️Usage and note:

- Spray thoroughly on both sides of leaves, stems, branches, and diseased areas...

- Use regularly to prevent disease with high efficiency. In case the fungus has infected the internal plant tissue, the effectiveness is much lower, it is necessary to use it with active ingredients with systemic properties to increase the effectiveness of disease prevention and treatment.

- The dosage must be exact as recommended by the manufacturer to avoid the development of pesticide resistance.

- Do not mix with pesticides containing sulfur and calcium.

Comply with safety and protection principles in labor.

▪️Application: The pesticide is used to prevent diseases on leaves, stems, fruits, and roots of many crops such as rice, corn, vegetables, fruit trees, industrial crops,...

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